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Dithioesters: simple, tunable, cysteine-selective H(2)S donors

Dithioesters have a rich history in polymer chemistry for RAFT polymerizations and are readily accessible through different synthetic methods. Here we demonstrate that the dithioester functional group is a tunable motif that releases H(2)S upon reaction with cysteine and that structural and electron...

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Detalles Bibliográficos
Autores principales: Cerda, Matthew M., Newton, Turner D., Zhao, Yu, Collins, Brylee K., Hendon, Christopher H., Pluth, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368244/
https://www.ncbi.nlm.nih.gov/pubmed/30842844
http://dx.doi.org/10.1039/c8sc04683b