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Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes

The connection between Zika virus (ZIKV) and neurodevelopmental defects is widely recognized, although the mechanisms underlying the infectivity and pathology in primary human glial cells are poorly understood. Here we show that three isolated strains of ZIKV, an African strain MR766 (Uganda) and tw...

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Detalles Bibliográficos
Autores principales: Ojha, Chet Raj, Rodriguez, Myosotys, Karuppan, Mohan Kumar Muthu, Lapierre, Jessica, Kashanchi, Fatah, El-Hage, Nazira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368285/
https://www.ncbi.nlm.nih.gov/pubmed/30735502
http://dx.doi.org/10.1371/journal.pone.0208543