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Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes
The connection between Zika virus (ZIKV) and neurodevelopmental defects is widely recognized, although the mechanisms underlying the infectivity and pathology in primary human glial cells are poorly understood. Here we show that three isolated strains of ZIKV, an African strain MR766 (Uganda) and tw...
Autores principales: | Ojha, Chet Raj, Rodriguez, Myosotys, Karuppan, Mohan Kumar Muthu, Lapierre, Jessica, Kashanchi, Fatah, El-Hage, Nazira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368285/ https://www.ncbi.nlm.nih.gov/pubmed/30735502 http://dx.doi.org/10.1371/journal.pone.0208543 |
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