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Targeted lipopolysaccharide biosynthetic intermediate analysis with normal-phase liquid chromatography mass spectrometry

Lipopolysacharride (LPS) forms the outer leaflet of the outer membrane in Gram-negative bacteria and contributes to the permeability barrier and immune response. In this study, we established a method for monitoring the LPS biosynthetic intermediates of the Raetz pathway (lpxA-lpxK) in Escherichia c...

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Detalles Bibliográficos
Autores principales: Sawyer, William S., Wang, Lisha, Uehara, Tsuyoshi, Tamrakar, Pramila, Prathapam, Ramadevi, Mostafavi, Mina, Metzger, Louis E., Feng, Brian, Baxter Rath, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368293/
https://www.ncbi.nlm.nih.gov/pubmed/30735516
http://dx.doi.org/10.1371/journal.pone.0211803