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Involvement of the protein kinase Akt2 in insulin-stimulated Rac1 activation leading to glucose uptake in mouse skeletal muscle

Translocation of the glucose transporter GLUT4 to the sarcolemma accounts for glucose uptake in skeletal muscle following insulin administration. The protein kinase Akt2 and the small GTPase Rac1 have been implicated as essential regulators of insulin-stimulated GLUT4 translocation. Several lines of...

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Detalles Bibliográficos
Autores principales: Takenaka, Nobuyuki, Araki, Natsumi, Satoh, Takaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368313/
https://www.ncbi.nlm.nih.gov/pubmed/30735546
http://dx.doi.org/10.1371/journal.pone.0212219