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Identification of a bilirubin receptor that may mediate a component of cholestatic itch

Various pathologic conditions result in jaundice, a yellowing of the skin due to a buildup of bilirubin. Patients with jaundice commonly report experiencing an intense non-histaminergic itch. Despite this association, the pruritogenic capacity of bilirubin itself has not been described, and no bilir...

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Detalles Bibliográficos
Autores principales: Meixiong, James, Vasavda, Chirag, Green, Dustin, Zheng, Qin, Qi, Lijun, Kwatra, Shawn G, Hamilton, James P, Snyder, Solomon H, Dong, Xinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368403/
https://www.ncbi.nlm.nih.gov/pubmed/30657454
http://dx.doi.org/10.7554/eLife.44116