Longdaysin inhibits Wnt/β-catenin signaling and exhibits antitumor activity against breast cancer

BACKGROUND: CK1 is involved in regulating Wnt/β-catenin signaling and represents a promising target for the treatment of breast cancer. A purine derivative longdaysin has recently been identified as a novel modulator of cellular circadian rhythms through targeting the protein kinases CK1δ, CK1α, and...

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Detalles Bibliográficos
Autores principales: Xiong, Yanpeng, Zhou, Liang, Su, Zijie, Song, Jiaxing, Sun, Qi, Liu, Shan-Shan, Xia, Yuqing, Wang, Zhongyuan, Lu, Desheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368421/
https://www.ncbi.nlm.nih.gov/pubmed/30787621
http://dx.doi.org/10.2147/OTT.S193024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368421/
https://www.ncbi.nlm.nih.gov/pubmed/30787621
http://dx.doi.org/10.2147/OTT.S193024

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