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Longdaysin inhibits Wnt/β-catenin signaling and exhibits antitumor activity against breast cancer

BACKGROUND: CK1 is involved in regulating Wnt/β-catenin signaling and represents a promising target for the treatment of breast cancer. A purine derivative longdaysin has recently been identified as a novel modulator of cellular circadian rhythms through targeting the protein kinases CK1δ, CK1α, and...

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Detalles Bibliográficos
Autores principales:	Xiong, Yanpeng, Zhou, Liang, Su, Zijie, Song, Jiaxing, Sun, Qi, Liu, Shan-Shan, Xia, Yuqing, Wang, Zhongyuan, Lu, Desheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368421/ https://www.ncbi.nlm.nih.gov/pubmed/30787621 http://dx.doi.org/10.2147/OTT.S193024

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