Defective proteostasis in celiac disease as a new therapeutic target

Cystic fibrosis (CF) is a disease caused by loss-of-function mutations affecting the CF transmembrane conductance regulator (CFTR), a chloride channel. Recent evidence indicates that CFTR is inhibited by a gluten/gliadin-derived peptide (P31-43), causing an acquired state of CFTR inhibition within t...

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Detalles Bibliográficos
Autores principales: Maiuri, Luigi, Villella, Valeria R, Piacentini, Mauro, Raia, Valeria, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368542/
https://www.ncbi.nlm.nih.gov/pubmed/30737369
http://dx.doi.org/10.1038/s41419-019-1392-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368542/
https://www.ncbi.nlm.nih.gov/pubmed/30737369
http://dx.doi.org/10.1038/s41419-019-1392-9

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