The pro-apoptotic Bcl-2 family member Harakiri (HRK) induces cell death in glioblastoma multiforme

Harakiri (HRK) is a BH3-only protein of the Bcl-2 family and regulates apoptosis by interfering with anti-apoptotic Bcl-2 and Bcl-xL proteins. While its function is mainly characterized in the nervous system, its role in tumors is ill-defined with few studies demonstrating HRK silencing in tumors. I...

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Detalles Bibliográficos
Autores principales: Kaya-Aksoy, Ezgi, Cingoz, Ahmet, Senbabaoglu, Filiz, Seker, Fidan, Sur-Erdem, Ilknur, Kayabolen, Alisan, Lokumcu, Tolga, Sahin, Gizem Nur, Karahuseyinoglu, Sercin, Bagci-Onder, Tugba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368544/
https://www.ncbi.nlm.nih.gov/pubmed/30774992
http://dx.doi.org/10.1038/s41420-019-0144-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368544/
https://www.ncbi.nlm.nih.gov/pubmed/30774992
http://dx.doi.org/10.1038/s41420-019-0144-z

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