Exosome-mediated horizontal gene transfer occurs in double-strand break repair during genome editing

The CRISPR-Cas9 system has been successfully applied in many organisms as a powerful genome-editing tool. Undoubtedly, it will soon be applied to human genome editing, including gene therapy. We have previously reported that unintentional DNA sequences derived from retrotransposons, genomic DNA, mRN...

Descripción completa

Detalles Bibliográficos
Autores principales: Ono, Ryuichi, Yasuhiko, Yukuto, Aisaki, Ken-ichi, Kitajima, Satoshi, Kanno, Jun, Hirabayashi, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368560/
https://www.ncbi.nlm.nih.gov/pubmed/30775458
http://dx.doi.org/10.1038/s42003-019-0300-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368560/
https://www.ncbi.nlm.nih.gov/pubmed/30775458
http://dx.doi.org/10.1038/s42003-019-0300-2

Ejemplares similares