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Exosome-mediated horizontal gene transfer occurs in double-strand break repair during genome editing

The CRISPR-Cas9 system has been successfully applied in many organisms as a powerful genome-editing tool. Undoubtedly, it will soon be applied to human genome editing, including gene therapy. We have previously reported that unintentional DNA sequences derived from retrotransposons, genomic DNA, mRN...

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Detalles Bibliográficos
Autores principales:	Ono, Ryuichi, Yasuhiko, Yukuto, Aisaki, Ken-ichi, Kitajima, Satoshi, Kanno, Jun, Hirabayashi, Yoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368560/ https://www.ncbi.nlm.nih.gov/pubmed/30775458 http://dx.doi.org/10.1038/s42003-019-0300-2

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