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Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

During wound healing in adult mouse skin, hair follicles and then adipocytes regenerate. Adipocytes regenerate from myofibroblasts, a specialized contractile wound fibroblast. Here we study wound fibroblast diversity using single-cell RNA-sequencing. On analysis, wound fibroblasts group into twelve...

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Detalles Bibliográficos
Autores principales: Guerrero-Juarez, Christian F., Dedhia, Priya H., Jin, Suoqin, Ruiz-Vega, Rolando, Ma, Dennis, Liu, Yuchen, Yamaga, Kosuke, Shestova, Olga, Gay, Denise L., Yang, Zaixin, Kessenbrock, Kai, Nie, Qing, Pear, Warren S., Cotsarelis, George, Plikus, Maksim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368572/
https://www.ncbi.nlm.nih.gov/pubmed/30737373
http://dx.doi.org/10.1038/s41467-018-08247-x