Probing the Inhibition of Microtubule Affinity Regulating Kinase 4 by N-Substituted Acridones

Microtubule affinity regulating kinase 4 (MARK4) becomes a unique anti-cancer drug target as its overexpression is responsible for different types of cancers. In quest of novel, effective MARK4 inhibitors, some acridone derivatives were synthesized, characterized and evaluated for inhibitory activit...

Descripción completa

Detalles Bibliográficos
Autores principales: Voura, Maria, Khan, Parvez, Thysiadis, Savvas, Katsamakas, Sotiris, Queen, Aarfa, Hasan, Gulam Mustafa, Ali, Sher, Sarli, Vasiliki, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368574/
https://www.ncbi.nlm.nih.gov/pubmed/30737440
http://dx.doi.org/10.1038/s41598-018-38217-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368574/
https://www.ncbi.nlm.nih.gov/pubmed/30737440
http://dx.doi.org/10.1038/s41598-018-38217-8

Ejemplares similares