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Probing the Inhibition of Microtubule Affinity Regulating Kinase 4 by N-Substituted Acridones
Microtubule affinity regulating kinase 4 (MARK4) becomes a unique anti-cancer drug target as its overexpression is responsible for different types of cancers. In quest of novel, effective MARK4 inhibitors, some acridone derivatives were synthesized, characterized and evaluated for inhibitory activit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368574/ https://www.ncbi.nlm.nih.gov/pubmed/30737440 http://dx.doi.org/10.1038/s41598-018-38217-8 |