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The binding of Borealin to microtubules underlies a tension independent kinetochore-microtubule error correction pathway

Proper chromosome segregation depends upon kinetochore phosphorylation by the Chromosome Passenger Complex (CPC). Current models suggest the activity of the CPC decreases in response to the inter-kinetochore stretch that accompanies the formation of bi-oriented microtubule attachments, however littl...

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Detalles Bibliográficos
Autores principales: Trivedi, Prasad, Zaytsev, Anatoly V., Godzi, Maxim, Ataullakhanov, Fazly I., Grishchuk, Ekaterina L., Stukenberg, P. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368601/
https://www.ncbi.nlm.nih.gov/pubmed/30737408
http://dx.doi.org/10.1038/s41467-019-08418-4