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Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice

The aims of this study are to investigate the selective cytotoxic activity of supercritical carbon dioxide (scCO(2))-extracted freeze-dried leaf juice (FDLJ) of Carica papaya on squamous cell carcinoma (SCC25) cells, and to delineate the best small scale extraction parameters allowing maximal extrac...

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Detalles Bibliográficos
Autores principales: Khaw, Kooi-Yeong, Parat, Marie-Odile, Shaw, Paul Nicholas, Nguyen, Thao T. T., Pandey, Saurabh, Thurecht, Kristofer J., Falconer, James Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368614/
https://www.ncbi.nlm.nih.gov/pubmed/30737457
http://dx.doi.org/10.1038/s41598-018-37171-9