A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection

Class F receptors are considered valuable therapeutic targets due to their role in human disease, but structural changes accompanying receptor activation remain unexplored. Employing population and cancer genomics data, structural analyses, molecular dynamics simulations, resonance energy transfer-b...

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Detalles Bibliográficos
Autores principales: Wright, Shane C., Kozielewicz, Paweł, Kowalski-Jahn, Maria, Petersen, Julian, Bowin, Carl-Fredrik, Slodkowicz, Greg, Marti-Solano, Maria, Rodríguez, David, Hot, Belma, Okashah, Najeah, Strakova, Katerina, Valnohova, Jana, Babu, M. Madan, Lambert, Nevin A., Carlsson, Jens, Schulte, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368630/
https://www.ncbi.nlm.nih.gov/pubmed/30737406
http://dx.doi.org/10.1038/s41467-019-08630-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368630/
https://www.ncbi.nlm.nih.gov/pubmed/30737406
http://dx.doi.org/10.1038/s41467-019-08630-2

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