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Age-related Disturbances in DNA (hydroxy)methylation in APP/PS1 Mice

Brain aging has been associated with aberrant DNA methylation patterns, and changes in the levels of DNA methylation and associated markers have been observed in the brains of Alzheimer’s disease (AD) patients. DNA hydroxymethylation, however, has been sparsely investigated in aging and AD. We have...

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Detalles Bibliográficos
Autores principales: Chouliaras, Leonidas, Lardenoije, Roy, Kenis, Gunter, Mastroeni, Diego, Hof, Patrick R., van Os, Jim, Steinbusch, Harry W.M., van Leeuwen, Fred W., Rutten, Bart P.F., van den Hove, Daniel L.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368665/
https://www.ncbi.nlm.nih.gov/pubmed/30746282
http://dx.doi.org/10.1515/tnsci-2018-0028