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Effect of Nobiletin on Experimental Model of Epilepsy

BACKGROUND: The effects of nobiletin, a plant-derived flavonoid was examined against pentylenetetrazole (PTZ)-induced seizures. The study also aimed to assess whether nobiletin potentiated the effects of antiepileptic drug clonazepam (CZP). METHODS: PTZ (92 mg/kg, subcutaneous) was used to induce se...

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Detalles Bibliográficos
Autores principales: Yang, Baowang, Wang, Jing, Zhang, Ni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368667/
https://www.ncbi.nlm.nih.gov/pubmed/30746285
http://dx.doi.org/10.1515/tnsci-2018-0031