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Semaphorin4A causes loss of mature oligodendrocytes and demyelination in vivo
BACKGROUND: Inappropriate contact between the immune system and the central nervous system is thought to be a cause of demyelination. We previously reported the ability of the class IV semaphorin, Semaphorin4A (Sema4A), to induce apoptosis in human oligodendrocytes; however, these results have yet t...
Autores principales: | Chiou, Brian, Neely, Elizabeth, Kallianpur, Asha, Connor, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368782/ https://www.ncbi.nlm.nih.gov/pubmed/30736794 http://dx.doi.org/10.1186/s12974-019-1420-9 |
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