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Genomic prediction of tuberculosis drug-resistance: benchmarking existing databases and prediction algorithms

BACKGROUND: It is possible to predict whether a tuberculosis (TB) patient will fail to respond to specific antibiotics by sequencing the genome of the infecting Mycobacterium tuberculosis (Mtb) and observing whether the pathogen carries specific mutations at drug-resistance sites. This advancement h...

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Detalles Bibliográficos
Autores principales: Ngo, Tra-My, Teo, Yik-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368788/
https://www.ncbi.nlm.nih.gov/pubmed/30736750
http://dx.doi.org/10.1186/s12859-019-2658-z