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Genomic prediction of tuberculosis drug-resistance: benchmarking existing databases and prediction algorithms
BACKGROUND: It is possible to predict whether a tuberculosis (TB) patient will fail to respond to specific antibiotics by sequencing the genome of the infecting Mycobacterium tuberculosis (Mtb) and observing whether the pathogen carries specific mutations at drug-resistance sites. This advancement h...
Autores principales: | Ngo, Tra-My, Teo, Yik-Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368788/ https://www.ncbi.nlm.nih.gov/pubmed/30736750 http://dx.doi.org/10.1186/s12859-019-2658-z |
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