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Bazedoxifene as a novel GP130 inhibitor for Colon Cancer therapy

BACKGROUND: Interleukin-11 (IL-11), a dominant IL-6 family cytokine, is involved in tumorigenesis, tumor progression and differentiation in colon cancer cells. IL-11 signaling has been recently identified as a potential therapeutic target in colon cancer. Bazedoxifene, a third- generation selective...

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Detalles Bibliográficos
Autores principales: Wei, Jia, Ma, Ling, Lai, Yi-Hui, Zhang, Ruijie, Li, Huameng, Li, Chenglong, Lin, Jiayuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368818/
https://www.ncbi.nlm.nih.gov/pubmed/30736824
http://dx.doi.org/10.1186/s13046-019-1072-8