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The toxin from a ParDE toxin‐antitoxin system found in Pseudomonas aeruginosa offers protection to cells challenged with anti‐gyrase antibiotics

Toxin‐antitoxin systems are mediators of diverse activities in bacterial physiology. For the ParE‐type toxins, their reported role of gyrase inhibition utilized during plasmid‐segregation killing indicates they are toxic. However, their location throughout chromosomes leads to questions about functi...

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Detalles Bibliográficos
Autores principales: Muthuramalingam, Meenakumari, White, John C., Murphy, Tamiko, Ames, Jessica R., Bourne, Christina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368863/
https://www.ncbi.nlm.nih.gov/pubmed/30427086
http://dx.doi.org/10.1111/mmi.14165