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Co-expression of HIF-1α, MDR1 and LAPTM4B in peripheral blood of solid tumors

The hypoxic tumor microenvironment is the major contributor of chemotherapy resistance in solid tumors. One of the key regulators of hypoxic responses within the cell is the hypoxia inducible factor-1α (HIF-1α) that is involved in transcription of genes promoting cell survival and chemotherapy resis...

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Detalles Bibliográficos
Autores principales: Rehman, Zaira, Fahim, Ammad, Bhatti, Attya, Sadia, Hajra, John, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368972/
https://www.ncbi.nlm.nih.gov/pubmed/30746305
http://dx.doi.org/10.7717/peerj.6309