Systemically Administered Reovirus-Induced Downregulation of Hypoxia Inducible Factor-1α in Subcutaneous Tumors

Reovirus, which possesses a 10-segmented double-stranded RNA genome, mediates superior antitumor effects via not only virus replication in a tumor cell-specific manner but also other mechanisms distinct from virus replication. Several groups, including ours, reported the reovirus-mediated downregula...

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Detalles Bibliográficos
Autores principales: Hotani, Takuma, Mizuguchi, Hiroyuki, Sakurai, Fuminori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369106/
https://www.ncbi.nlm.nih.gov/pubmed/30788427
http://dx.doi.org/10.1016/j.omto.2018.12.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369106/
https://www.ncbi.nlm.nih.gov/pubmed/30788427
http://dx.doi.org/10.1016/j.omto.2018.12.012

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