Cargando…

Systemically Administered Reovirus-Induced Downregulation of Hypoxia Inducible Factor-1α in Subcutaneous Tumors

Reovirus, which possesses a 10-segmented double-stranded RNA genome, mediates superior antitumor effects via not only virus replication in a tumor cell-specific manner but also other mechanisms distinct from virus replication. Several groups, including ours, reported the reovirus-mediated downregula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hotani, Takuma, Mizuguchi, Hiroyuki, Sakurai, Fuminori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369106/ https://www.ncbi.nlm.nih.gov/pubmed/30788427 http://dx.doi.org/10.1016/j.omto.2018.12.012

Ejemplares similares

Involvement of Protein Kinase R in Double-Stranded RNA-Induced Proteasomal Degradation of Hypoxia Inducible Factor-1α
por: Hotani, Takuma, et al.
Publicado: (2023)

Proteolytic Disassembly of Viral Outer Capsid Proteins Is Crucial for Reovirus-Mediated Type-I Interferon Induction in Both Reovirus-Susceptible and Reovirus-Refractory Tumor Cells
por: Katayama, Yuki, et al.
Publicado: (2015)

miR-27b antagonizes BMP signaling in early differentiation of human induced pluripotent stem cells
por: Lim, Jaeeun, et al.
Publicado: (2021)

Downregulation of Hypoxia-Inducible Factor-1α by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats
por: Hu, Yiping, et al.
Publicado: (2020)

Adenovirus vector-based vaccine for infectious diseases
por: Sakurai, Fuminori, et al.
Publicado: (2022)

Tumor‐targeted fluorescence labeling systems for cancer diagnosis and treatment
por: Tazawa, Hiroshi, et al.
Publicado: (2022)

Salidroside ameliorated hypoxia‐induced tumorigenesis of BxPC‐3 cells via downregulating hypoxia‐inducible factor (HIF)‐1α and LOXL2
por: Chen, Xiaoping, et al.
Publicado: (2019)

Sodium fluoride induces apoptosis through the downregulation of hypoxia-inducible factor-1α in primary cultured rat chondrocytes
por: MENG, HONGMEI, et al.
Publicado: (2014)

Hypoxia‐inducible factor‐1 α deletion in myeloid lineage attenuates hypoxia‐induced pulmonary hypertension
por: Kojima, Hiroshi, et al.
Publicado: (2019)

Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells
por: Fuady, Jerry H., et al.
Publicado: (2016)

Cannabidiol Suppresses Angiogenesis and Stemness of Breast Cancer Cells by Downregulation of Hypoxia-Inducible Factors-1α
por: Jo, Min Jee, et al.
Publicado: (2021)

Novel duck reovirus exhibits pathogenicity to specific pathogen-free chickens by the subcutaneous route
por: Yu, Kexiang, et al.
Publicado: (2021)

Efficient antitumor effects of a novel oncolytic adenovirus fully composed of species B adenovirus serotype 35
por: Ono, Ryosuke, et al.
Publicado: (2021)

Hypoxia‐Inducible Factor‐2α Signaling in the Skeletal System
por: Mendoza, Sarah V, et al.
Publicado: (2023)

Dicer functions as an antiviral system against human adenoviruses via cleavage of adenovirus-encoded noncoding RNA
por: Machitani, Mitsuhiro, et al.
Publicado: (2016)

Correction: Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells
por: Fuady, Jerry H., et al.
Publicado: (2017)

Downregulation of Proline Hydroxylase 2 and Upregulation of Hypoxia-Inducible Factor 1α are Associated with Endometrial Cancer Aggressiveness
por: Zhu, Chengcheng, et al.
Publicado: (2019)

Potent inhibition of tumoral hypoxia-inducible factor 1α by albendazole
por: Pourgholami, Mohammad H, et al.
Publicado: (2010)

Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestine
por: Ozawa, Tatsuya, et al.
Publicado: (2015)

Absorption Kinetics of Subcutaneously Administered Ceftazidime in Hypoperfused Guinea Pigs
por: Ebihara, Tsuyoshi, et al.
Publicado: (2014)

Oncolytic Reovirus in Canine Mast Cell Tumor
por: Hwang, Chung Chew, et al.
Publicado: (2013)

Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells
por: Sethumadhavan, Shalini, et al.
Publicado: (2017)

Syngeneic monoclonal antiidiotype can induce cellular immunity to reovirus
Publicado: (1984)

NAD+ depletion enhances reovirus-induced oncolysis in multiple myeloma
por: Kennedy, Barry E., et al.
Publicado: (2022)

Effects of hypoxia inducible factor-1α on apoptotic inhibition and glucocorticoid receptor downregulation by dexamethasone in AtT-20 cells
por: Zhang, Chenran, et al.
Publicado: (2015)

Bioavailability of IgG Administered by the Subcutaneous Route
por: Berger, Melvin, et al.
Publicado: (2013)

Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability
por: Gradel, A. K. J., et al.
Publicado: (2018)

Recombinant Lactococcus lactis Expressing Grass Carp Reovirus VP6 Induces Mucosal Immunity Against Grass Carp Reovirus Infection
por: Wang, Nan, et al.
Publicado: (2022)

Metastatic breast tumors downregulate miR-145 regulating the hypoxia-induced vasculogenic mimicry
por: Contreras-Sanzón, Estefania, et al.
Publicado: (2023)

Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction
por: Nakamori, Daiki, et al.
Publicado: (2017)

Neonatal Gene Therapy for Hemophilia B by a Novel Adenovirus Vector Showing Reduced Leaky Expression of Viral Genes
por: Iizuka, Shunsuke, et al.
Publicado: (2017)

Effects of pre-existing anti-adenovirus antibodies on transgene expression levels and therapeutic efficacies of arming oncolytic adenovirus
por: Ono, Ryosuke, et al.
Publicado: (2022)

Hypoxia Induces Autophagic Cell Death through Hypoxia-Inducible Factor 1α in Microglia
por: Yang, Zhao, et al.
Publicado: (2014)

Hypoxia-inducible factor-1α and -2α are expressed in most rectal cancers but only hypoxia-inducible factor-1α is associated with prognosis
por: Rasheed, S, et al.
Publicado: (2009)

Hypoxia-inducible factor-1α and -2α are expressed in most rectal cancers but only hypoxia-inducible factor-1α is associated with prognosis
por: Rasheed, S, et al.
Publicado: (2009)

Recognition of Reovirus RNAs by the Innate Immune System
por: Abad, Andrew T., et al.
Publicado: (2020)

Pharmacokinetic study of omacetaxine mepesuccinate administered subcutaneously to patients with advanced solid and hematologic tumors
por: Nemunaitis, John, et al.
Publicado: (2012)

CONGENITAL INFECTIONS WITH REOVIRUS
por: Hashimi, Ali, et al.
Publicado: (1966)

The Interplay of Reovirus with Autophagy
por: Chiu, Hung-Chuan, et al.
Publicado: (2014)

Hypoxia, Hypoxia-Inducible Factor-1α, and Innate Antileishmanial Immune Responses
por: Schatz, Valentin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_71u2i0r4ej64dth43usluco6gi