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Walnut phenolic extracts reduce telomere length and telomerase activity in a colon cancer stem cell model

BACKGROUND/OBJECTIVES: Telomeres are located at the chromosomal ends and progressively shortened during each cell cycle. Telomerase, which is regulated by hTERT and c-MYC, maintains telomeric DNA sequences. Especially, telomerase is active in cancer and stem cells to maintain telomere length for rep...

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Detalles Bibliográficos
Autores principales: Shin, Phil-Kyung, Zoh, Yoonchae, Choi, Jina, Kim, Myung-Sunny, Kim, Yuri, Choi, Sang-Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Nutrition Society and the Korean Society of Community Nutrition 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369112/
https://www.ncbi.nlm.nih.gov/pubmed/30788057
http://dx.doi.org/10.4162/nrp.2019.13.1.58