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Role of FOXO3 Activated by HIV-1 Tat in HIV-Associated Neurocognitive Disorder Neuronal Apoptosis

There are numerous types of pathological changes in human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND), including apoptosis of neurons. HIV-1 transactivator of transcription (Tat) protein, which is encoded by HIV-1, may promote apoptosis in HAND. Forkhead box O3 (FOXO3) is...

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Detalles Bibliográficos
Autores principales: Dong, Huaqian, Ye, Xiang, Zhong, Li, Xu, Jinhong, Qiu, Jinhua, Wang, Jun, Shao, Yiming, Xing, Huiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369160/
https://www.ncbi.nlm.nih.gov/pubmed/30778283
http://dx.doi.org/10.3389/fnins.2019.00044