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Differential Regulation of Human Treg and Th17 Cells by Fatty Acid Synthesis and Glycolysis

In this study we examined the metabolic requirements of human T helper cells and the effect of manipulating metabolic pathways in Th17 and Treg cells. The Th17:Treg cell axis is dysregulated in a number of autoimmune or inflammatory diseases and therefore it is of key importance to identify novel st...

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Detalles Bibliográficos
Autores principales: Cluxton, Deborah, Petrasca, Andreea, Moran, Barry, Fletcher, Jean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369198/
https://www.ncbi.nlm.nih.gov/pubmed/30778354
http://dx.doi.org/10.3389/fimmu.2019.00115