Cargando…

Differential Regulation of Human Treg and Th17 Cells by Fatty Acid Synthesis and Glycolysis

In this study we examined the metabolic requirements of human T helper cells and the effect of manipulating metabolic pathways in Th17 and Treg cells. The Th17:Treg cell axis is dysregulated in a number of autoimmune or inflammatory diseases and therefore it is of key importance to identify novel st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cluxton, Deborah, Petrasca, Andreea, Moran, Barry, Fletcher, Jean M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369198/ https://www.ncbi.nlm.nih.gov/pubmed/30778354 http://dx.doi.org/10.3389/fimmu.2019.00115

Ejemplares similares

Gut Microflora Modulates Th17/Treg Cell Differentiation in Experimental Autoimmune Prostatitis via the Short-Chain Fatty Acid Propionate
por: Du, He-Xi, et al.
Publicado: (2022)

Human Vδ2(+) γδ T Cells Differentially Induce Maturation, Cytokine Production, and Alloreactive T Cell Stimulation by Dendritic Cells and B Cells
por: Petrasca, Andreea, et al.
Publicado: (2014)

The immunomodulation role of Th17 and Treg in renal transplantation
por: Huang, Dan-Lei, et al.
Publicado: (2023)

Thrombospondin-1/CD47 Interaction Regulates Th17 and Treg Differentiation in Psoriasis
por: Rodríguez-Jiménez, Pedro, et al.
Publicado: (2019)

The Alterations in and the Role of the Th17/Treg Balance in Metabolic Diseases
por: Zhang, Siwen, et al.
Publicado: (2021)

Editorial: Dysregulation of Th17 and Treg cells in autoimmune diseases
por: Astier, Anne L., et al.
Publicado: (2023)

Metabolic Disturbance and Th17/Treg Imbalance Are Associated With Progression of Gingivitis
por: Wang, Weijie, et al.
Publicado: (2021)

The Treg/Th17 Axis: A Dynamic Balance Regulated by the Gut Microbiome
por: Omenetti, Sara, et al.
Publicado: (2015)

Gut Microbiota as Regulators of Th17/Treg Balance in Patients With Myasthenia Gravis
por: Chen, Pan, et al.
Publicado: (2021)

Editorial: The importance of Th17/Treg imbalance in asthma and COPD development and progression
por: Lopes, Fernanda Degobbi T. Q. S., et al.
Publicado: (2022)

Insulin-binding protein-5 down-regulates the balance of Th17/Treg
por: Zhu, Mengyuan, et al.
Publicado: (2022)

The MS Remyelinating Drug Bexarotene (an RXR Agonist) Promotes Induction of Human Tregs and Suppresses Th17 Differentiation In Vitro
por: Gaunt, Christopher M., et al.
Publicado: (2021)

Bile acid metabolites control Th17 and Treg cell differentiation
por: Hang, Saiyu, et al.
Publicado: (2019)

Th17/Treg Imbalance in Chronic Obstructive Pulmonary Disease: Clinical and Experimental Evidence
por: Lourenço, Juliana Dias, et al.
Publicado: (2021)

Fresh Evidence for Platelets as Neuronal and Innate Immune Cells: Their Role in the Activation, Differentiation, and Deactivation of Th1, Th17, and Tregs during Tissue Inflammation
por: Ponomarev, Eugene D.
Publicado: (2018)

Cytomegalovirus infection disrupts the influence of short-chain fatty acid producers on Treg/Th17 balance
por: Chin, Ning, et al.
Publicado: (2022)

Th17/Treg-Related Transcriptional Factor Expression and Cytokine Profile in Patients With Rheumatoid Arthritis
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2020)

ICS/LABA Combined With Subcutaneous Immunotherapy Modulates the Th17/Treg Imbalance in Asthmatic Children
por: Dai, Huan, et al.
Publicado: (2022)

Bcl-3 regulates the function of Th17 cells through raptor mediated glycolysis metabolism
por: Liu, Hui, et al.
Publicado: (2022)

Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis
por: Zhang, Qian, et al.
Publicado: (2020)

Altered Th17/Treg Ratio in Peripheral Blood of Systemic Lupus Erythematosus but Not Primary Antiphospholipid Syndrome
por: Álvarez-Rodríguez, Lorena, et al.
Publicado: (2019)

IL-21 Induces an Imbalance of Th17/Treg Cells in Moderate-to-Severe Plaque Psoriasis Patients
por: Shi, Yuling, et al.
Publicado: (2019)

Plumbagin Ameliorates Collagen-Induced Arthritis by Regulating Treg/Th17 Cell Imbalances and Suppressing Osteoclastogenesis
por: Wang, Tingyu, et al.
Publicado: (2019)

Leonurine Regulates Treg/Th17 Balance to Attenuate Rheumatoid Arthritis Through Inhibition of TAZ Expression
por: Du, Yan-Yi, et al.
Publicado: (2020)

T Cell Metabolism: A New Perspective on Th17/Treg Cell Imbalance in Systemic Lupus Erythematosus
por: Shan, Juan, et al.
Publicado: (2020)

Stigmasterol Restores the Balance of Treg/Th17 Cells by Activating the Butyrate-PPARγ Axis in Colitis
por: Wen, Shuting, et al.
Publicado: (2021)

Predominantly Antibody-Deficient Patients With Non-infectious Complications Have Reduced Naive B, Treg, Th17, and Tfh17 Cells
por: Edwards, Emily S. J., et al.
Publicado: (2019)

The Dynamics of Treg/Th17 and the Imbalance of Treg/Th17 in Clonorchis sinensis-Infected Mice
por: Yan, Chao, et al.
Publicado: (2015)

Extracellular Vesicles From Kidney Allografts Express miR-218-5p and Alter Th17/Treg Ratios
por: Rutman, Alissa K., et al.
Publicado: (2022)

The IDO–AhR Axis Controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection
por: de Araújo, Eliseu Frank, et al.
Publicado: (2017)

Retraction: Plumbagin Ameliorates Collagen-Induced Arthritis by Regulating Treg/Th17 Cell Imbalances and Suppressing Osteoclastogenesis
Publicado: (2020)

Combination Treatment With Metformin and Tacrolimus Improves Systemic Immune Cellular Homeostasis by Modulating Treg and Th17 Imbalance
por: Lee, Soon Kyu, et al.
Publicado: (2021)

Human chorionic gonadotropin promotes murine Treg cells and restricts pregnancy-harmful proinflammatory Th17 responses
por: Lentz, Lea S., et al.
Publicado: (2022)

Commentary: T cell metabolism: a new perspective on Th17/Treg cell imbalance in systemic lupus erythematosus
por: Jin, Jiamei, et al.
Publicado: (2023)

Endotoxin tolerance modulates TREG and TH17 lymphocytes protecting septic mice
por: Andrade, Mariana M.C., et al.
Publicado: (2019)

Neutralization of interleukin-17 suppresses allergic rhinitis symptoms by downregulating Th2 and Th17 responses and upregulating the Treg response
por: Gu, Zhao Wei, et al.
Publicado: (2017)

Imbalanced Th17/Treg in peripheral blood of adult patients with immunoglobulin A vasculitis nephritis
por: Xue, Xue, et al.
Publicado: (2021)

AhR Ligands Differentially Regulate miRNA-132 Which Targets HMGB1 and to Control the Differentiation of Tregs and Th-17 Cells During Delayed-Type Hypersensitivity Response
por: Abdulla, Osama A., et al.
Publicado: (2021)

Semaphorin 4D Induces an Imbalance of Th17/Treg Cells by Activating the Aryl Hydrocarbon Receptor in Ankylosing Spondylitis
por: Xie, Jianmin, et al.
Publicado: (2020)

Galectin-9 Regulates Monosodium Urate Crystal-Induced Gouty Inflammation Through the Modulation of Treg/Th17 Ratio
por: Mansour, Adel Abo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j6cnr7hbkkpqsu9tfgqd8i1pqb