Exosomal Transmission of MicroRNA from HCV Replicating Cells Stimulates Transdifferentiation in Hepatic Stellate Cells

The mechanism by which hepatitis C virus (HCV) causes fibrosis and other chronic liver diseases remains poorly understood. Previously, we observed that HCV infection induces microRNA-192 (miR-192) expression, which in turn upregulates transforming growth factor β1 (TGF-β1) in hepatocytes. In this st...

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Detalles Bibliográficos
Autores principales: Kim, Ji Hyun, Lee, Chang Ho, Lee, Seong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369229/
https://www.ncbi.nlm.nih.gov/pubmed/30753992
http://dx.doi.org/10.1016/j.omtn.2019.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369229/
https://www.ncbi.nlm.nih.gov/pubmed/30753992
http://dx.doi.org/10.1016/j.omtn.2019.01.006

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