Hippocampal GAD67 Transduction Using rAAV8 Regulates Epileptogenesis in EL Mice

Gene therapy has been employed as a therapeutic approach for intractable focal epilepsies. Considering the potential of focal GABAergic neuromodulation in regulating epileptogenesis, the GABA-producing enzyme, γ-aminobutyric acid decarboxylase 67 (GAD67), is highly suitable for epilepsy therapy. The...

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Detalles Bibliográficos
Autores principales: Shimazaki, Kuniko, Kobari, Takashi, Oguro, Keiji, Yokota, Hidenori, Kasahara, Yuko, Murashima, Yoshiya, Watanabe, Eiju, Kawai, Kensuke, Okada, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369250/
https://www.ncbi.nlm.nih.gov/pubmed/30788386
http://dx.doi.org/10.1016/j.omtm.2018.12.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369250/
https://www.ncbi.nlm.nih.gov/pubmed/30788386
http://dx.doi.org/10.1016/j.omtm.2018.12.012

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