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Sex Differences in Antidepressant Effect of Sertraline in Transgenic Mouse Models

The main purpose of this study is to explore sex differences in the antidepressant effect of sertraline in genetic knockout or overexpression estrogen-synthesizing enzyme aromatase (Ar) gene mouse models in the forced swim test (FST). Our results demonstrated a significant reduction of depression-li...

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Detalles Bibliográficos
Autores principales: Ma, Lei, Xu, Yong, Jiang, Wei, Li, Yuhong, Zhang, Xinzhu, Wang, Gang, Li, Rena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369353/
https://www.ncbi.nlm.nih.gov/pubmed/30778289
http://dx.doi.org/10.3389/fncel.2019.00024