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Sex Differences in Antidepressant Effect of Sertraline in Transgenic Mouse Models
The main purpose of this study is to explore sex differences in the antidepressant effect of sertraline in genetic knockout or overexpression estrogen-synthesizing enzyme aromatase (Ar) gene mouse models in the forced swim test (FST). Our results demonstrated a significant reduction of depression-li...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369353/ https://www.ncbi.nlm.nih.gov/pubmed/30778289 http://dx.doi.org/10.3389/fncel.2019.00024 |