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Automated Clinical Grade Expansion of Regulatory T Cells in a Fully Closed System

Adoptive transfer of T regulatory cells (Treg) has been successfully exploited in the context of graft-versus-host disease, transplantation, and autoimmune disease. For the majority of applications, clinical administration of Treg requires laborious ex vivo expansion and typically involves open hand...

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Detalles Bibliográficos
Autores principales: Marín Morales, José Manuel, Münch, Nadine, Peter, Katja, Freund, Daniel, Oelschlägel, Uta, Hölig, Kristina, Böhm, Thea, Flach, Anne-Christine, Keßler, Jörg, Bonifacio, Ezio, Bornhäuser, Martin, Fuchs, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369367/
https://www.ncbi.nlm.nih.gov/pubmed/30778344
http://dx.doi.org/10.3389/fimmu.2019.00038