Cargando…

Automated Clinical Grade Expansion of Regulatory T Cells in a Fully Closed System

Adoptive transfer of T regulatory cells (Treg) has been successfully exploited in the context of graft-versus-host disease, transplantation, and autoimmune disease. For the majority of applications, clinical administration of Treg requires laborious ex vivo expansion and typically involves open hand...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marín Morales, José Manuel, Münch, Nadine, Peter, Katja, Freund, Daniel, Oelschlägel, Uta, Hölig, Kristina, Böhm, Thea, Flach, Anne-Christine, Keßler, Jörg, Bonifacio, Ezio, Bornhäuser, Martin, Fuchs, Anke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369367/ https://www.ncbi.nlm.nih.gov/pubmed/30778344 http://dx.doi.org/10.3389/fimmu.2019.00038

Ejemplares similares

T-cell receptor-α repertoire of CD8+ T cells following allogeneic stem cell transplantation using next-generation sequencing
por: Link-Rachner, Cornelia S., et al.
Publicado: (2019)

Next Generation Biobanking: Employing a Robotic System for Automated Mononuclear Cell Isolation
por: Fuchs, Yannick F., et al.
Publicado: (2023)

Long-Term Mixed Chimerism After Ex Vivo/In Vivo T Cell-Depleted Allogeneic Hematopoietic Cell Transplantation in Patients With Myeloid Neoplasms
por: Ruhnke, Leo, et al.
Publicado: (2021)

Symptomatic central nervous system involvement in adult patients with acute myeloid leukemia
por: Alakel, Nael, et al.
Publicado: (2017)

Fully automated expansion and activation of clinical-grade natural killer cells for adoptive immunotherapy
por: GRANZIN, MARKUS, et al.
Publicado: (2015)

Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia
por: Wobus, Manja, et al.
Publicado: (2015)

Potential of TCR sequencing in graft-versus-host disease
por: Goel, Manisha, et al.
Publicado: (2022)

P528: CAN MULTIPARAMETRIC FLOW CYTOMETRY OF PERIPHERAL BLOOD CHALLENGE BONE MARROW ANALYSES FOR DETECTION OF MEASURABLE RESIDUAL DISEASE IN PATIENTS WITH ACUTE MYELOID LEUKEMIA?
por: Schadt, Jonas, et al.
Publicado: (2023)

Tight coupling expansion and fully inhomogeneous magnetic fields
por: Giovannini, Massimo
Publicado: (2006)

Fully closed cell sorter for immune cell therapy manufacturing
por: Matsumoto, Masahiro, et al.
Publicado: (2023)

Luspatercept restores SDF-1-mediated hematopoietic support by MDS-derived mesenchymal stromal cells
por: Wobus, Manja, et al.
Publicado: (2021)

A Fully Automated Pipeline for Normative Atrophy in Patients with Neurodegenerative Disease
por: Rummel, Christian, et al.
Publicado: (2018)

Improvement of cell freezing technologies: towards a fully closed process
por: Polès-Lahille, Aurore, et al.
Publicado: (2011)

Impact of partially and fully closed eaves on house entry rates by mosquitoes
por: Mburu, Monicah M., et al.
Publicado: (2018)

Fully Closed-Loop Insulin Delivery in Patients Undergoing Pancreatic Surgery
por: Krutkyte, Gabija, et al.
Publicado: (2023)

Fully automated preoperative segmentation of temporal bone structures from clinical CT scans
por: Neves, C. A., et al.
Publicado: (2021)

Fully integrated, fully automated generation of short tandem repeat profiles
por: Tan, Eugene, et al.
Publicado: (2013)

Flow cytometry datasets consisting of peripheral blood and bone marrow samples for the evaluation of explainable artificial intelligence methods
por: Thrun, Michael C., et al.
Publicado: (2022)

Culture expansion of adipose derived stromal cells. A closed automated Quantum Cell Expansion System compared with manual flask-based culture
por: Haack-Sørensen, Mandana, et al.
Publicado: (2016)

Purification and Ex Vivo Expansion of Fully Functional Salivary Gland Stem Cells
por: Nanduri, Lalitha S.Y., et al.
Publicado: (2014)

Development of fully-automated synthesis systems
por: Sugawara, Tohru, et al.
Publicado: (1994)

Fully automated closed-loop insulin delivery in adults with type 2 diabetes: an open-label, single-center, randomized crossover trial
por: Daly, Aideen B., et al.
Publicado: (2023)

Chemical Composition and Antioxidant Potential of Five Algae Cultivated in Fully Controlled Closed Systems
por: Nova, Paulo, et al.
Publicado: (2023)

Search for resonant $WZ$ production in the fully leptonic final state with the ATLAS detector
por: Freund, Benjamin
Publicado: (2020)

Reproducible measurable residual disease detection by multiparametric flow cytometry in acute myeloid leukemia
por: Röhnert, Maximilian A., et al.
Publicado: (2022)

Immunotherapy in Type 1 Diabetes: A Shorter but More Winding Road?
por: Bonifacio, Ezio
Publicado: (2012)

Fully automated life support: an implementation and feasibility pilot study in healthy pigs
por: Klingert, Wilfried, et al.
Publicado: (2018)

Detection of virus-specific intrathecally synthesised immunoglobulin G with a fully automated enzyme immunoassay system
por: Schubert, Jörg, et al.
Publicado: (2007)

Feasibility of fully automated closed-loop glucose control using continuous subcutaneous glucose measurements in critical illness: a randomized controlled trial
por: Leelarathna, Lalantha, et al.
Publicado: (2013)

Unit 3 - The multipolar expansion of magnetic field
por: Todesco, Ezio
Publicado: (2020)

Gauge fixing in fully gauge-invariant field theory of closed bosonic and Neveu-Schwarz strings
por: de Alwis, S P, et al.
Publicado: (1988)

Feasibility of Outpatient Fully Integrated Closed-Loop Control: First studies of wearable artificial pancreas
por: Kovatchev, Boris P., et al.
Publicado: (2013)

A Fully Integrated Closed‐Loop System Based on Mesoporous Microneedles‐Iontophoresis for Diabetes Treatment
por: Li, Xiangling, et al.
Publicado: (2021)

Wireless, fully implantable cardiac stimulation and recording with on-device computation for closed-loop pacing and defibrillation
por: Ausra, Jokubas, et al.
Publicado: (2022)

VMXi: a fully automated, fully remote, high-flux in situ macromolecular crystallography beamline
por: Sanchez-Weatherby, Juan, et al.
Publicado: (2019)

Fully and semi-automated shape differentiation in NGSolve
por: Gangl, Peter, et al.
Publicado: (2020)

Towards the fully automated monitoring of ecological communities
por: Besson, Marc, et al.
Publicado: (2022)

Closing the Gap between Single Molecule and Bulk FRET Analysis of Nucleosomes
por: Gansen, Alexander, et al.
Publicado: (2013)

A closed-form expansion for the conditional expectations of the extended CIR process
por: Rujivan, Sanae, et al.
Publicado: (2022)

Reliability and Influence on Decision Making of fully-automated vs. semi-automated Software Packages for Procedural Planning in TAVI
por: Meyer, Alexander, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_akugm4ffejj5v8uf0u0im4dedl