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Regulation of cytoskeleton and adhesion signaling in osteoclasts by tetraspanin CD82

We used a myeloid-specific Cre to conditionally delete CD82 in mouse osteoclasts and their precursors. In contrast to global loss of CD82 (gKO), conditional loss of CD82 (cKO) in osteoclasts does not affect cortical bone, osteoblasts, or adipocytes. CD82 loss results in greater trabecular volume and...

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Detalles Bibliográficos
Autores principales: Bergsma, Alexis, Ganguly, Sourik S., Wiegand, Mollie E., Dick, Daniel, Williams, Bart O., Miranti, Cindy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369370/
https://www.ncbi.nlm.nih.gov/pubmed/30788390
http://dx.doi.org/10.1016/j.bonr.2019.100196