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Regulation of cytoskeleton and adhesion signaling in osteoclasts by tetraspanin CD82
We used a myeloid-specific Cre to conditionally delete CD82 in mouse osteoclasts and their precursors. In contrast to global loss of CD82 (gKO), conditional loss of CD82 (cKO) in osteoclasts does not affect cortical bone, osteoblasts, or adipocytes. CD82 loss results in greater trabecular volume and...
Autores principales: | Bergsma, Alexis, Ganguly, Sourik S., Wiegand, Mollie E., Dick, Daniel, Williams, Bart O., Miranti, Cindy K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369370/ https://www.ncbi.nlm.nih.gov/pubmed/30788390 http://dx.doi.org/10.1016/j.bonr.2019.100196 |
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