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Excessive Oxidative Stress Contributes to Increased Acute ER Stress Kidney Injury in Aged Mice
The aged kidney is susceptible to acute injury due presumably to its decreased ability to handle additional challenges, such as endoplasmic reticulum (ER) stress. This was tested by giving tunicamycin, an ER stress inducer, to either old or young mice. Injection of high dose caused renal failure in...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369482/ https://www.ncbi.nlm.nih.gov/pubmed/30809321 http://dx.doi.org/10.1155/2019/2746521 |