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Excessive Oxidative Stress Contributes to Increased Acute ER Stress Kidney Injury in Aged Mice

The aged kidney is susceptible to acute injury due presumably to its decreased ability to handle additional challenges, such as endoplasmic reticulum (ER) stress. This was tested by giving tunicamycin, an ER stress inducer, to either old or young mice. Injection of high dose caused renal failure in...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaoyan, Zhang, Ruihua, Huang, Lianghu, Zheng, Zihan, Vlassara, Helen, Striker, Gary, Zhang, Xiaoyan, Guan, Youfei, Zheng, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369482/ https://www.ncbi.nlm.nih.gov/pubmed/30809321 http://dx.doi.org/10.1155/2019/2746521

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