Centrosome guides spatial activation of Rac to control cell polarization and directed cell migration

Directed cell migration requires centrosome-mediated cell polarization and dynamical control of focal adhesions (FAs). To examine how FAs cooperate with centrosomes for directed cell migration, we used centrosome-deficient cells and found that loss of centrosomes enhanced the formation of acentrosom...

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Detalles Bibliográficos
Autores principales: Cheng, Hung-Wei, Hsiao, Cheng-Te, Chen, Yin-Quan, Huang, Chi-Ming, Chan, Seng-I, Chiou, Arthur, Kuo, Jean-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369537/
https://www.ncbi.nlm.nih.gov/pubmed/30737247
http://dx.doi.org/10.26508/lsa.201800135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369537/
https://www.ncbi.nlm.nih.gov/pubmed/30737247
http://dx.doi.org/10.26508/lsa.201800135

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