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Centrosome guides spatial activation of Rac to control cell polarization and directed cell migration
Directed cell migration requires centrosome-mediated cell polarization and dynamical control of focal adhesions (FAs). To examine how FAs cooperate with centrosomes for directed cell migration, we used centrosome-deficient cells and found that loss of centrosomes enhanced the formation of acentrosom...
Autores principales: | Cheng, Hung-Wei, Hsiao, Cheng-Te, Chen, Yin-Quan, Huang, Chi-Ming, Chan, Seng-I, Chiou, Arthur, Kuo, Jean-Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369537/ https://www.ncbi.nlm.nih.gov/pubmed/30737247 http://dx.doi.org/10.26508/lsa.201800135 |
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