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Axl kinase drives immune checkpoint and chemokine signalling pathways in lung adenocarcinomas

Axl receptor tyrosine kinase is involved in the growth and metastasis and is an indicator of poor prognosis in several cancers including lung cancers. Although a mitogen-activated protein kinase (MAPK) pathway and an epithelial-to-mesenchymal transition (EMT) program are critical, molecular mechanis...

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Detalles Bibliográficos
Autores principales: Tsukita, Yoko, Fujino, Naoya, Miyauchi, Eisaku, Saito, Ryoko, Fujishima, Fumiyoshi, Itakura, Koji, Kyogoku, Yorihiko, Okutomo, Koji, Yamada, Mitsuhiro, Okazaki, Tatsuma, Sugiura, Hisatoshi, Inoue, Akira, Okada, Yoshinori, Ichinose, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369543/
https://www.ncbi.nlm.nih.gov/pubmed/30744655
http://dx.doi.org/10.1186/s12943-019-0953-y