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Axl kinase drives immune checkpoint and chemokine signalling pathways in lung adenocarcinomas
Axl receptor tyrosine kinase is involved in the growth and metastasis and is an indicator of poor prognosis in several cancers including lung cancers. Although a mitogen-activated protein kinase (MAPK) pathway and an epithelial-to-mesenchymal transition (EMT) program are critical, molecular mechanis...
Autores principales: | Tsukita, Yoko, Fujino, Naoya, Miyauchi, Eisaku, Saito, Ryoko, Fujishima, Fumiyoshi, Itakura, Koji, Kyogoku, Yorihiko, Okutomo, Koji, Yamada, Mitsuhiro, Okazaki, Tatsuma, Sugiura, Hisatoshi, Inoue, Akira, Okada, Yoshinori, Ichinose, Masakazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369543/ https://www.ncbi.nlm.nih.gov/pubmed/30744655 http://dx.doi.org/10.1186/s12943-019-0953-y |
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