A Neutralizing Aptamer to TGFBR2 and miR-145 Antagonism Rescue Cigarette Smoke- and TGF-β-Mediated CFTR Expression

Transforming growth factor β (TGF-β), signaling induced by cigarette smoke (CS), plays an important role in the progression of airway diseases, like chronic bronchitis associated with chronic obstructive pulmonary disease (COPD), and in smokers. Chronic bronchitis is characterized by reduced mucocil...

Descripción completa

Detalles Bibliográficos
Autores principales: Dutta, Rajib K., Chinnapaiyan, Srinivasan, Rasmussen, Lawrence, Raju, S. Vamsee, Unwalla, Hoshang J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369566/
https://www.ncbi.nlm.nih.gov/pubmed/30595527
http://dx.doi.org/10.1016/j.ymthe.2018.11.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369566/
https://www.ncbi.nlm.nih.gov/pubmed/30595527
http://dx.doi.org/10.1016/j.ymthe.2018.11.017

Ejemplares similares