Straightforward Regeneration of Reduced Flavin Adenine Dinucleotide Required for Enzymatic Tryptophan Halogenation

[Image: see text] Flavin-dependent halogenases are known to regioselectively introduce halide substituents into aromatic moieties, for example, the indole ring of tryptophan. The process requires halide salts and oxygen instead of molecular halogen in the chemical halogenation. However, the reduced...

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Detalles Bibliográficos
Autores principales: Ismail, Mohamed, Schroeder, Lea, Frese, Marcel, Kottke, Tilman, Hollmann, Frank, Paul, Caroline E., Sewald, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369659/
https://www.ncbi.nlm.nih.gov/pubmed/30775067
http://dx.doi.org/10.1021/acscatal.8b04500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369659/
https://www.ncbi.nlm.nih.gov/pubmed/30775067
http://dx.doi.org/10.1021/acscatal.8b04500

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