Chromatin features constrain structural variation across evolutionary timescales

The potential impact of structural variants includes not only the duplication or deletion of coding sequences, but also the perturbation of noncoding DNA regulatory elements and structural chromatin features, including topological domains (TADs). Structural variants disrupting TAD boundaries have be...

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Detalles Bibliográficos
Autores principales: Fudenberg, Geoff, Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369792/
https://www.ncbi.nlm.nih.gov/pubmed/30659153
http://dx.doi.org/10.1073/pnas.1808631116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369792/
https://www.ncbi.nlm.nih.gov/pubmed/30659153
http://dx.doi.org/10.1073/pnas.1808631116

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