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Combined administration of PTX and S-HM-3 in TPGS/Solutol micelle system for oncotarget therapy

BACKGROUND: S-HM-3 is a tumor angiogenesis inhibitor with short half-life (25 min). In this present, TPGS/Solutol polymeric micelles was prepared to load together insoluble paclitaxel (PTX) and soluble S-HM-3, expecting to together deliver them to the tumor site with long-circulating, targeting func...

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Detalles Bibliográficos
Autores principales: Li, Weiguang, Xue, Jianpeng, Xu, Hanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369847/
https://www.ncbi.nlm.nih.gov/pubmed/30799919
http://dx.doi.org/10.2147/IJN.S189864