Refining eligibility criteria for amyotrophic lateral sclerosis clinical trials

OBJECTIVE: To assess the effect of eligibility criteria on exclusion rates, generalizability, and outcome heterogeneity in amyotrophic lateral sclerosis (ALS) clinical trials and to assess the value of a risk-based inclusion criterion. METHODS: A literature search was performed to summarize the elig...

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Detalles Bibliográficos
Autores principales: van Eijk, Ruben P.A., Westeneng, Henk-Jan, Nikolakopoulos, Stavros, Verhagen, Iris E., van Es, Michael A., Eijkemans, Marinus J.C., van den Berg, Leonard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369899/
https://www.ncbi.nlm.nih.gov/pubmed/30626653
http://dx.doi.org/10.1212/WNL.0000000000006855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369899/
https://www.ncbi.nlm.nih.gov/pubmed/30626653
http://dx.doi.org/10.1212/WNL.0000000000006855

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